Combined Celiac Ganglia and Plexus Neurolysis Shortens Survival, Without Benefit, vs Plexus Neurolysis Alone

Celiac plexus neurolysis.

Pancreatic cancer is the tenth most common malignancy and the fourth cause of cancerrelated death in Western countries. Because 5year survival in referral centers is less than 30%, clinical management of most patients involves palliation of the symptoms of which 90% are weight loss, jaundice, and pain. While jaundice related to biliary obstruction can be palliated by means of endoscopic therapy...

EUS-guided celiac plexus neurolysis and celiac plexus block.

Pancreatic cancer and chronic pancreatitis commonly produce pain that is difficult to control.1,2 Initial therapy with nonsteroidal anti-inflammatory agents (NSAIDs) is often inadequate and necessitates opioid administration. Although opioids effectively relieve pain, they are associated with dry mouth, constipation, nausea, vomiting, drowsiness, delirium, and may impair immune function.3,4 In ...

EUS-guided celiac plexus block/neurolysis.

Hemorrhagic gastritis and duodenitis following celiac plexus neurolysis.

INTRODUCTION Neurolytic celiac plexus block is a well established intervention to palliate pain, and it potentially improves quality of life in patients suffering from an upper abdominal malignancy, specifically pancreatic cancer. METHODS We describe a 61-year-old female with a history of pancreatic cancer, unexplained transfusion dependent anemia with a normal recent upper endoscopy, and abd...

Pulmonary embolism following celiac plexus block and neurolysis.

Treatment of acute pain in chronic disease requires the physician to choose from an arsenal of pain management techniques tailored to the individual patient. Celiac plexus block and neurolysis are commonly employed for the management of chronic abdominal pain, especially in debilitating conditions such as cancer or chronic pancreatitis. The procedure is safe, well tolerated, and produces few co...